UNFOLDING THE MYSTERIES OF GENETIC SCIENCES IN INCURABLE DISEASES LIKE CORONARY ARTERY DISEASES, CANCER, & RAREST OF THE RARE DISEASES LIKE MOYAMOYA, SLE, TAKAYASU ETC.

-The prees conferencE held in Ghy Dt-3rd July

Systemic Lupus Erythematosus (SLE)- rare incurable dreaded Disease – present Medical Science has failed to cure it.

Baruah Applied Human Genetic Engineering- has successfully cured it.

Dr.Dhani Ram Baruah, FRCSGlas.

          Systemic Lupus Erythematosus (SLE) is a chronic potentially fatal autoimmune disease. SLE is a complex disorder resulting from the production of antibodies that attack the DNA and proteins within healthy cells and the generation of circulating immune complexes. The complications from this affect multiple organs and are potentially life-threatening.

          Joints, skin, kidney, brain, and membranes of the lung, heart and gastro-intestinal tract are the major organs clinically affected in SLE patients. The symptoms are often vague, can be mild or severe and are often unrelated to laboratory tests. A patient can have many lupus symptoms in a lifetime. Women and non-Caucasians are disproportionately affected and SLE is most common in women of child-bearing age although it has been reported in all ages. The incidence is about 1 in 200 people in America. Among children, SLE occurs three times more commonly in females than in males. In the 60% of SLE patients who experience onset between puberty and the fourth decade of life, the female to male ratio is 9:1. The disorder is three times more common in African American blacks than American Caucasians and more common in Asians. The cause of SLE was said to be unknown, however our research work has suggested that it is of genetic origin as we have cured SLE patient with Baruah Applied Human Genetic Engineering. It was thought that hormonal and /or environmental factors are few factors affecting  SLE, but it is not true. As corrective therapies such as hormone replacement or supportive treatment do not cure SLE.

          Many researchers had suspected that it is a genetic mutation that disrupts the body's waste disposal mechanism in cells. SLE is caused by a hyperactive immune system that attacks a person's own protein recognising it as a foreign material. One reason for this is poor adrenal function. Adrenal steroids modulate the immune system. When there is insufficient steroid levels, the immune system goes haywire. Whatever hypothesis of possible causes have been postulated in the past and present, no one was or is able to cure SLE, till we have discovered the Baruah biological molecules which intercepts the cells destructive autoimmune pathway. Fatigue on light exertion, light sensitivity, skin rash, ulcers in mouth specially on soft palate and on nasal septum, susceptibility to infection with slow recovery, muscle pain, mild or high fever, sore throat, numbness, headache, tingling or burning sensation in extremities, joint pain/ stiffness/swelling, chest pain, atherosclerosis, respiratory distress, uro-genital infections, nephropathy, anemia, low white cell/platelet counts and several other disorders are the usual symptoms. Diagnosing SLE can be a difficult and slow process. It may take months or even years for doctors to diagnose this complex disease accurately. A tentative diagnosis can be made through examining a patient's medical history and performing a physical examination and screening tests (positive SLE-ANA >40). Once SLE is suspected, additional tests are valuable to confirm or rule it out. Elevated ESR or high levels of ANA are the common laboratory test indicative of SLE. The most useful test is to identify certain autoantibodies often present in the blood of SLE patients. For example, the antinuclear antibody (ANA) test is commonly used to look for autoantibodies that react against components of the nucleus of the patient’s own cells. In addition, there are blood tests for individual types of autoantibodies that are more specific for SLE. Treatment for SLE in medical science is not specific and not available, where it is treated with steroids, certain hormonal therapies, diet, plant steroids, immunosuppressive drugs and timely treatment for any infection and so on. But 100% cure was not yet known.

   Mrs.Dipika Vakil, a Mumbai resident  was suffered from SLE, diagnosed and treated with steroids in Mumbai by well known expert doctors whereas, this treatment is detrimental to this disease. She put on weight by 7kgs in two months. Biopsy of the kidney suggested that she suffered from Lupus kidney and there was absolutely no way that she can survive too long. On 6^th June, she attended my clinic in Mumbai. She came to Baruah Institute at Sonapur, Assam and we treated her with Baruah Applied human genetic engineering using Baruah molecules. She is cured which is proven by autoantibody tests carried out at Micro Diagnostics.