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Unfolding
Mysteries
of Human
Genetic ScienceS
Applied human genetic engineering is beyond the reach of
todays medical sciences. Medical science is wrong by one
hundred percentage, in particular reference to treatment
of Coronary artery disease (CAD).Cardio-vascular science
as a whole is mistaken by 85% in terms of
investigation & treatment of cardio-vascular diseases.
Heart disease particularly coronary artery disease
has become an epidemic and conventional treatment like
angioplasty, stenting & bypass surgery, are found to
give no permanent remedy. In reality, these procedures
are becoming a mismatch and injurious to heart &
health causes premature death. Coronary artery disease
becomes aggressive a fter
these procedures as it has been observed that symptoms
become more noticeable and aggressive compared to
the period before these procedures. It takes 15-20years
to produce the symptoms and look for medical help.
Whatever, medical help is offered to the patient, these
appeared to be harmful, which I have described in this
chapter.
In recent years, scientists & clinicians together have
thought to solve the problem permanently by doing gene
therapy to cure the heart disease by angiogenesis which
has failed totally. The process of angiogenesis is no
where nearer to cure this disease.
Clinicians did not understand the process of pathology
of coronary artery disease and further failed to
understand that this disease is generalized disease
involving entire arterial system producing partial or
complete blockages causing prematurely aging of cells.
This disease is created by mysterious process which has
been found out by us by our extensive research work.
Scientists are thinking in recent days, angiogenesis
will be the answer. However, our studies have suggested
that angiogenesis may take place, but the new blood
vessels will be diseased unless the mutation of
responsible genes are corrected. Our further studies on
genetic sciences have suggested that incurable diseases
such as diabetes, hypertension , arthritis, rarest of
the rare diseases are all having genetic origin.
It has been classified into two- 1.inheritable- either
recessive or dominant type. In recessive, always
expressed clinically where both copies of mistaken genes
are involved, therefore, always it is expressed in
diseased form. In dominant-heterozygous type , single
copy of mistaken genes are expressed, therefore, it may
or may not expressed in diseased form. The second type
of classification, any disease of incurable type is
expressed due to mutation of the gene, which was not
been found out by any genetic scientist in the past and
not due to recessive or dominant genes. It is due to
mutation of single or group of genes expressed
sometimes in the life time when conditions become
favourable. Genes are inheritable units, interacting
with each other, lying as beads on strands of DNA,
interacting with each other and use their strength for
mental & physical growth of the individual. I term the
strength of the genes is due to the type of protein &
its structure. DNA strands are found in nucleus & DNA
does the work of mental & physical growth in beneficiary
or diseased form through RNA particularly in form of
m-RNA which is used in translation process at cytosol.
In the nucleus, process of transcription takes place
where synthesis of RNA takes place to inherit exact
replication of the properties of DNA in form of single
strand. Therefore, it has been understood that whatever,
command given by the DNA, that will be carried by RNA
into cytoplasm and ultimate work
will be done by RNA by synthesizing new structure of the
protein, either to use for tissues in respective organs
or in destructive form, express in disease form bringing
premature death. Therefore, if we do the sequencing of
m-RNA, which will give the exact idea what is happening
during transcription. There is another incidence always
happened during transcription that is splicing where
separation of intron & exon takes place. Exons go along
with m-RNA holding responsibility of ultimate action of
m-RNA. Mistaken splicing causes wrong translation, which
ultimately leads to errors in metabolic pathways
leading to mistaken protein synthesis and expressed in
particular diseased form. The following few events are
to be noted in genetic sciences and its mysteries are
unfolded by us as the following.
Till today, genetic scientist have not been able to find
out how the coronary artery disease has been initiated
and cure it permanently. Of course, the fact remains
cure of any disease is possible, once the causes are
known. I am surprised to see that millions & millions of
dollars are spent on research to find out the causes and
curative treatment of the diseases. But the results are
found to be zero. All these researchers on this planet
ended with publications, no application has been found
for the welfare of human race. Therefore, in recent
years, heart disease has become an epidemic. In10 years
time, I am predicting, each & every family will suffer
from heart disease unless, they accept my applied human
genetic engineering.
 What
are our findings?
Mutation is the term used in genetic sciences over a
period of last few years, which causes particularly
malignancy. We could not find any references stating
that mutation of particular gene causes coronary artery
diseases. I was shocked to see when, we have carried out
sequencing of identified genes causing CAD and
de-mutation of these genes have been done using Baruah
biological molecules within 24 hours of its use.
DNA does not work directly, but it does its work through
RNA involving the process of translation &
transcription. Therefore, we can understand work of DNA
or type of DNA we know from the analysis of work of
m-RNA. The process of transcription always takes place
within the nucleus and process of translation takes
place within cytosol, outside nucleus. The process of
translation is involved with m-RNA and ribosomes, which
signals the synthesis of new proteins within the
endoplasmic reticulum, works as a factory and to
disburse this, the protein for mental and physical
growth, golgi bodies come into the picture. We found
that during our experimental studies that the process
of translation change its genetic codes in disease
conditions, which ultimately codes wrong amino acid,
synthesizing wrong proteins.
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Copyright© DR Dhani Ram Baruah Heart City2007
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