UNFOLDING THE MYSTERIES OF GENETIC SCIENCES IN INCURABLE DISEASES LIKE CORONARY ARTERY DISEASES, CANCER, & RAREST OF THE RARE DISEASES LIKE MOYAMOYA, SLE, TAKAYASU ETC.

Inventor’s moutH

Applied human genetic engineering is beyond the reach of today's medical sciences. Entire medical science is wrong by 80% in particular reference to cardiovascular science which is wrong by 90-95%.. My observation has further suggested that investigations and treatment in cardio-vascular diseases and cancer remained to be absolutely inadequate. This should be at molecular level and unfortunately, it is not understood by clinicians. At this point, I would like to site following facts-

        When coronary artery is blocked, patient feels pain and breathlessness, usually ECG, blood chemistry analysis with angiography are investigative techniques. I feel it is too late to do any treatment to provide a permanent relief to the patient

         CT scan, MRI are used to detect cancer. The tumour should be more than 4-5mm when it is detected by these methods and it is too late. By this time, cancer cells have been migrated to the body.

          We are becoming expert to detect coronary artery disease and cancer 20-25 years before it is expressed clinically. Now with Baruah applied human genetic engineering, we can eradicate these dreaded diseases including diabetes and hypertension, and rarest of the rare diseases like SLE, Moyamoya, Takayasu.

I started my cardiac surgery on 13th July 1978 in Belfast, Royal Victoria Hospital, and continued to work in several heart hospitals in Scotland, England, Sweden, and other scandinavian countries. Before, I came to cardiac surgery, I became a master in general surgery in Republic of Ireland in 1974 till 1978.

  However, it should have been more in numbers, but I could not do it because 75% of my time, I am spending in research in the field of cardio-vascular sciences. I was the first one to invent and develop biological heart valves using ox pericardium., which are anatomically constructed to achieve physiological performance demonstrating in vitro and in vivo durability of 92.8patient’s years.

  not require anticoagulant in aortic position and did not produce cavitation in mitral position. Therefore, use of anticoagulant even in mitral position is made to be minimal.

  recognized in cardio-vascular field as “HEART VALVE MAN “ in addition to cardiac surgeon.

  During my cardiac surgical procedure, I have observed the following:-

          .          Coronary artery disease (CAD) is not a localized disease confined to heart only, it is a generalized disease involving entire arterial tree. Therefore, it makes no sense doing bypass surgery if someone thinks that he has done a great job leaving the other blockages in peripheral arteries untouched.

          .      At the end of every bypass surgery, I always tell my theatre sister that I have done injustice to this patient as I knew that bypass surgery does more damage to heart and health than doing any good to it. I also knew by performing bypass surgery, I have brought his death forward than normally, it should have happened.

  clinicians and scientist do not know. I became very much involved mentally to undertake the research work in this field, which I have undertaken in April 1997.

  which was constructed anatomically to achieve physiological performance. I was the first one to develop stentless mitral and aortic heart valve mimicking the native heart valves.

  Heart’ in International Conference of Artificial Circulation in Germany, where I have shown that pig is the only animal genetically closer to human for experimental purpose and organ transplantation and not non-human primates. I found social behaviour, anatomy, physiology, hematology, bacteriology are similar to human. Any experiment surgical or medical- carried out on pigs, the datas are always comparable with human, therefore one should not hesitate to apply this experimental results on human directly, it will definitely work.

  was the first one to demonstrate that  hyperacute rejection can be overcome by using antigen suppression agent (ASA) which was design and developed by me 11years ago. Immunosuppressive drugs have no role to play to overcome hyperacute rejection.This is the major barrier for xenotransplantation, which we have overcome and made xenotransplantation possible.

  According to cardiac surgery training protocol, one has to be master in general surgery before, he enters into cardiac surgical training. So I became master in general surgery before I entered into cardiac surgery program. I did general surgery in Ireland and Cardiac surgery in UK, Sweden & other Scandenavian countries.

  Infirmary, Scotland, I made a statement that bypass surgery is genetically mismatch surgical procedure, injurious to heart and health, leaves the patients with uncertain future & leads to premature death.

  bradycardia. Bradycardia is a symptom of underlying disease, usually blockages of coronary arteries. I describe as a following:- A tired horse is whipped by his master to run faster and he became so exhausted that he drops dead, similarly a diseased heart is made to run by a permanent pacemaker and it cannot run, therefore, ceased to function prematurely. Hence permanent pacemaker should not be used.

         The adequate ventricular activities only can be achieved by demutating the responsible genes by using applied human genetic engineering, where Baruah biological molecules are highly essential.

 

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